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NCT07853417
Special Stains in Assessment of Bone Marrow Fibrosis
Conditions: Bone Marrow Fibrosis
Sex: All
Healthy volunteers: No
Enrollment: 60
Sponsor: Assiut University
Summary
This cross-sectional study aims to compare Picrosirius Red, Masson's Trichrome, and Reticulin stains for the detection and assessment of bone marrow fibrosis in trephine biopsy specimens.
Eligibility Criteria
Inclusion Criteria:
* \- Adequate bone marrow trephine biopsy tissue with sufficient well-fixed, well-preserved paraffin-embedded material for all required stains
* Cases with suspected or established marrow fibrosis and variable degrees of fibrosis
* Availability of relevant clinical and pathological information
Exclusion Criteria:
* \- Inadequate, fragmented, poorly fixed, or autolyzed tissue
* Unsuitable paraffin blocks due to processing artifacts
* Missing or insufficient clinical or pathological data required for analysis
Source: ClinicalTrials.gov (NCT07853417). StuddyBuddy aggregates publicly available trial information.