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Recruiting NCT07856706

A Single Ascending Dose, and Food Effect Study of ABBV-7828 in Healthy Adults

Conditions: Healthy Subjects

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 60
Sponsor: AbbVie

Location: Acpru /Id# 283545 Grayslake Illinois

Summary

This study is to evaluate safety, tolerability, pharmacokinetics and effect of food on ABBV-7828 compared to placebo in healthy adult participants.

Eligibility Criteria

Inclusion Criteria: * Individuals between 18 to 65 years of age at the time of screening. * BMI is \= 32.0 kg/m2. * A condition of general good health, based upon the results of a medical history, physical evaluations, vital signs, laboratory profile and a 12-lead ECG. Exclusion Criteria: * History of epilepsy, any clinically significant cardiac, respiratory (except mild asthma as a child), renal, hepatic, gastrointestinal, hematologic or psychiatric disease or disorder, or any uncontrolled medical illness. * Has any clinically significant ECG abnormalities including the following: * Evidence of 2nd or 3rd degree atrial ventricular (AV) block at screening visit or upon initial confinement * QT interval corrected for heart rate (QTc) using Fridericia's correction formula (QTcF) \> 450 msec (males) or \> 460 msec (females) at screening visit or upon initial confinement. * History of any clinically significant sensitivity or allergy to any medication or food. * History of or active medical condition(s) or surgical procedure(s) that might affect gastrointestinal motility, pH, or absorption.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07856706). StuddyBuddy aggregates publicly available trial information.