Radiological Intervention for Childhood Extra-Hepatic Portal Vein Obstruction

This study evaluates the safety and effectiveness of percutaneous portal vein recanalization (PVR) with stent placement, with or without transjugular intrahepatic portosystemic shunt (TIPS), in restoring portal flow and improving clinical outcomes in children and adolescents with chronic extrahepatic portal vein obstruction (EHPVO). The trial will assess technical feasibility, patency rates, and the reduction of complications such as variceal bleeding, ascites, and thrombocytopenia.

Inclusion Criteria: 1. Pediatric patients (aged \< 17 years) diagnosed with chronic extrahepatic portal vein obstruction (EHPVO) without cirrhosis. 2. Presence of refractory portal hypertension complications (e.g., recurrent variceal bleeding, symptomatic hypersplenism/thrombocytopenia, or refractory ascites) or portal cavernoma cholangiopathy Exclusion Criteria: 1. Pre-existing liver disease. 2. Other causes of portal hypertension.