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NCT07868003
Objective Depth-of-Focus Changes During Light Adjustable Lens UV Adjustments
Conditions: Light Adjustable Lens, Objective Depth of Focus
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 20
Sponsor: Clarity Eye Institute
Location: Lumea Barrie Ontario
Summary
This observational pilot study will examine how a person's vision changes during the routine adjustment and finalization of a Light Adjustable Lens (LAL) after surgery. The study will focus on objective depth of focus, measured using iTrace wavefront analyzer, which describes how clearly a person can see at different distances. This is a non-invasive eye test that will be used alongside the standard lens adjustment process. This study will help researchers understand why some patients achieve unexpectedly good near or intermediate vision after LAL adjustments despite being targeted for emmetropia.
Eligibility Criteria
Inclusion Criteria:
* Adults ≥18 years of age.
* Scheduled to undergo bilateral cataract extraction with LAL implantation as standard-of-care.
* Able to provide written informed consent.
* Able to comply with study visits and required assessments throughout the LAL adjustment and lock-in sequence.
Exclusion Criteria:
* Presence of ocular comorbidities in either eye that may affect visual outcomes or wavefront measurements, including but not limited to glaucoma, age-related macular degeneration, diabetic retinopathy, corneal disease, amblyopia, or prior refractive surgery.
* Intraoperative complications affecting IOL positioning, centration, or stability.
* Inability to obtain reliable iTrace measurements due to inadequate fixation or poor measurement quality.
* Participation in another interventional ophthalmic clinical study.
Source: ClinicalTrials.gov (NCT07868003). StuddyBuddy aggregates publicly available trial information.