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Completed NCT07870018

Clinical Research Study to Evaluate Stain Removal and Whitening Improvement

Conditions: Tooth Whitening, Tooth Discoloration

Sex: All
Ages: 18 Years – 70 Years
Healthy volunteers: Yes
Phase: PHASE2
Enrollment: 75
Sponsor: Colgate Palmolive

Location: Consumer Research Consulting, LLC Melbourne Florida

Summary

The objective of this clinical research study is to evaluate the stain removal and whitening improvement of a toothpaste containing Vitamin C and 1100 ppm F as sodium fluoride as compared to a matching placebo toothpaste (identically formulated without Vitamin C ) in adults

Eligibility Criteria

Inclusion Criteria: * Signed Informed Consent Form; * Male and female subjects, aged 18-70, inclusive; * Good general health and good oral health based on the opinion of the study investigator; * Presence of all permanent natural anterior teeth (no veneers /crowns /restorations that may interfere with this study scoring procedures ); * A minimum mean of 1 .5 ≥ determined by the Interproximal Modified Lobene (IML ) Stain Index; * Minimum average VITA 3D-Master Extended Bleachedguide shade score of 17 ≥ or darker; * Available for the duration of the study; * Clinical evidence of a tendency to form extrinsic stain on anterior teeth Exclusion Criteria: * Presence of orthodontic appliances /retainers involving scorable teeth; * Presence of partial removable /fixed dentures and /or restorations involving scorable teeth; * Tumor (s ) of the soft or hard tissues of the oral cavity; * Obvious signs of periodontal disease rampant caries, or any condition that the dental examiner considers exclusionary from the study; * Five or more carious lesions requiring immediate care; * Use of antibiotics, stain-inducing medications, and /or on any prescription that might interfere with the study outcome; * Concurrent participation in another clinical study; * Self-reported pregnancy and /or lactating women; * Have used professional whitening product within one (1 ) year or had a dental prophylaxis (professional dental cleaning ) within thirty (30 ) days - prior to the start of the study; * History of allergies to oral care /personal care consumer products or their ingredients; * History of alcohol and /or drug abuse.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07870018). StuddyBuddy aggregates publicly available trial information.