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Not Yet Recruiting NCT07873164

Vagal Auricular Stimulation for Motion Sickness

Conditions: Chronic Nausea

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 115
Sponsor: Spaulding Rehabilitation Hospital

Location: Spaulding Rehabilitation Hospital, 300 First Avenue Boston Massachusetts

Summary

This study aims to understand the mechanisms underlying nausea response in the brain stem, and the effect of vagal nerve stimulation on nausea.

Eligibility Criteria

Inclusion Criteria: * Age 18-65 years old (inclusive) * Ability to give written consent and participate in behavioral intervention in English * Avoidance of alcohol, nicotine, and caffeine for 24 hours prior to study session * Motion Sickness Susceptibility Questionnaire (MSSQ) percentile score \> 60. * Adequate visual, hearing, cognitive, and physical ability Exclusion Criteria: * Chronic nausea due to medications or gastrointestinal conditions * Prior or current history of seizures * Severe autonomic dysfunction * No active clinical acupuncture therapy * History of arrhythmias * Endorses any contraindications to MRI * Body weight of 450 lbs or greater or BMI of 32 kg/m2 or greater (limit of MRI table) * History any serious medical condition (e.g., cancer) * Pregnancy/breastfeeding within the last 8 weeks * Uncontrolled diabetes (indicated by HbA1c ³ 7%) by chart * Narcotic analgesics greater than three days per week * Illicit drugs or opioid usage * Cannabinoid use greater than three days per week * Intellectual disability by history * Illiteracy * Inability to provide informed consent * Any other condition interfering with study requirements, according to the investigator

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07873164). StuddyBuddy aggregates publicly available trial information.