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NCT07873242
A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants
Conditions: Muscle Soreness
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Enrollment: 600
Sponsor: Reckitt Benckiser Healthcare (UK) Limited
Location: Curion Insights LLC Deerfield Illinois
Summary
The purpose of the research study is to better understand the factors that impact pain experience in adult (18+ years) marathon runners participating in the 2026 Chicago Marathon and to better understand if topically applied menthol provides effective pain relief and impacts quality-of-life outcomes when used during the marathon, in the Recovery Zone immediately after the marathon, or during post-race recovery.
The main questions the study aims to answer are:
* Does topically applied menthol (gel and roll-on formats) reduce pain when applied in the Recovery Zone immediately after a marathon?
* What are the sensory attributes (e.g., cooling sensation) of topically applied menthol (gel and roll-on) when used in the Recovery Zone immediately after a marathon?
* How do participants assess the effects of topically applied menthol products used during and/or after a marathon on pain relief, performance, recovery, and sleep-related quality-of-life outcomes? Researchers will evaluate participant-reported pre- and post-application pain scores in the Recovery Zone immediately following the marathon and post-race outcomes to assess analgesic effectiveness, sensory attributes, and quality-of-life outcomes associated with Biofreeze use.
Participants will:
* Provide documented informed consent prior to participation.
* Self-select to use Biofreeze products during and/or after the race.
* Complete one or both of the following:
1. End of Race Questionnaire (includes pain score before and after Biofreeze application, sensory assessments, and demographics).
2. Post-Race Questionnaire (includes retrospective recall of pain relief, product use, sensory experience, sleep-related outcomes and demographic data).
Eligibility Criteria
Inclusion Criteria:
1. Participant has provided documented informed consent.
2. Participant aged 18 years and above.
3. Participant is an entrant into the Chicago marathon 2026.
4. Participant has self-selected to use Biofreeze during the race or during immediate recovery.
5. Comprehension of and able to read English.
Exclusion Criteria:
1\. Employee of Sponsor or Agency/ vendor collecting the data
Source: ClinicalTrials.gov (NCT07873242). StuddyBuddy aggregates publicly available trial information.