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Completed
NCT07883174
Motion Capture in Box and Bloks Test
Conditions: Healthy, Parkinson Disease, Stroke, Upper Extremity Paresis, Adults
Sex: All
Ages: 35 Years – 85 Years
Healthy volunteers: Yes
Enrollment: 105
Sponsor: IRCCS San Raffaele Roma
Location: IRCCS San Raffaele Roma Italy
Summary
This study aims not only to develop a standardized protocol for performing the targeted BBT but also to assess synchronized parameters: kinematic (using IMUs) and electrophysiological (EMG) data. In this context, the pilot study aims to standardize the instrumented BBT for the objective evaluation of joint kinematics and muscle activations in the upper limb of healthy subjects. After establishing normative movement data, the study will focus on characterizing pathological upper limb movements in individuals with Parkinson's disease and post-stroke, comparing the obtained data with normative references.
Eligibility Criteria
All participants who have signed the informed consent for the study and meeting the inclusion and exclusion criteria will be considered eligible. Each of the participants belonging to the three groups has to meet the following inclusion and exclusion criteria:
Control group (CG)
Inclusion Criteria:
* Age between 35 and 85 years old;
* Right-handed.
Exclusion Criteria:
* having pathologies affecting the upper limb function;
* having cognitive and/or severe visual deficit.
Parkinson group (PG)
Inclusion Criteria:
* diagnosis of idiopathic PD by UK Brain Bank criteria;
* Hoehn and Yahr (H\&Y) stage 2-3;
* aged between 35 and 85 years old;
* moderate disease-related upper limb motor performance deficit (i.e., Unified Parkinson's Disease Rating Scale (UPDRS) Part II, items 8, 9, 10, 11, 12, 16 =2-3; Unified Parkinson's Disease Rating Scale (UPDRS) Part III, items 20, 21, 22, 23, 24, 25 =2-3).
Exclusion Criteria:
* inability to understand study instructions;
* severe visual deficit;
* coexisting disabling neurological or orthopedic disorders at upper limb;
* previous brain surgery.
Stroke group (SG)
Inclusion Criteria:
* hemiparesis evaluated
* Fugl-Meyer Assessment Upper Limb (FMA-UL) ranging between moderate (22\
Source: ClinicalTrials.gov (NCT07883174). StuddyBuddy aggregates publicly available trial information.