AYUrvedic Foot Massage for Symtoms of Taxane-induced Peripheral nEuroPathy

Chemotherapy-induced peripheral neuropathy (CIPN) affects approximately 40% of patients treated with taxanes. These agents may cause burning pain, paresthesia, numbness, and loss of proprioceptive sensitivity, which can reduce well-being and impair quality of life.In this context, implementing non-pharmacological interventions, such as foot treatment/manipulation proposed in this project, represents a promising area to explore complementary therapies with minimal toxicity and low cost for symptom management.

Inclusion Criteria: * Age ≥ 18 anni * Diagnosis of carcinoma with ongoing treatment or treatment completed within the previous 6 months with taxanes (paclitaxel/docetaxel). * Grade 1-2 sensory-motor peripheral neuropathy (NCI-CTCAE v5). * Able to walk independently. * Written informed consent. Exclusion Criteria: * Pre-existing diabetic neuropathy * Foot ulcers or infections * Central neurological disorders * Concomitant specific treatment for CINP including other complementary medicine. Occasional over the counter drugs such as NSIDs or pain killer are allowed. Any other clinical condition that, at the discretion of the physician or practitioner, may contraindicate participation in the study procedures.