A Study to Evaluate the Efficacy and Safety of TP-06 for PCED

Capellion is a Phase 2 trial comparing TP-06 2.0% with Vehicle in up to 32 adults with persistent corneal epithelial defects. Participants will receive treatment for 8 weeks and be followed for 2 additional weeks to assess corneal healing and safety.

Inclusion Criteria: * Able and willing to provide written informed consent * Presence of a non-infected persistent corneal epithelial defect (PCED) in one eye that has failed to heal after at least 10 days of appropriate standard-of-care treatment * Stable lesion size between Screening and Baseline as assessed by the Investigator Exclusion Criteria: * Active ocular infection in either eye * Corneal perforation or high risk of corneal perforation * Severe eyelid abnormalities * Ocular or eyelid surgery in the study eye within 3 months prior to Baseline (unless PCED was caused by surgery) * Use of prohibited ophthalmic medications or procedures as defined in the protocol * Any condition that, in the Investigator's judgment, would interfere with study participation or interpretation of results Note: Additional exclusion criteria apply, as defined in the protocol