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Not Yet Recruiting NCT07888036

Neutrophil Activation and NETosis in Sepsis

Conditions: Sepsis, Septic Shock

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 85
Sponsor: Assiut University

Summary

This prospective observational study aims to evaluate neutrophil activation markers and circulating citrullinated histone H3 levels in adult patients with sepsis or septic shock.

Eligibility Criteria

Inclusion Criteria: * \- Adults aged 18 years or older * Patients fulfilling sepsis or septic shock criteria * Enrollment within 24 hours of diagnosis or ICU admission * Written informed consent Exclusion Criteria: * \- Known hematological malignancy * Known chronic liver disease with significant coagulopathy * Pre-existing hemostatic disorders * Therapeutic anticoagulation before enrollment

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07888036). StuddyBuddy aggregates publicly available trial information.