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Active Not Recruiting
NCT07890974
Tai Chi Training for Persons With Multiple Sclerosis.
Conditions: Multiple Sclerosis (MS) - Relapsing-remitting
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 35
Sponsor: Karolinska Institutet
Location: Karolinska Institutet Stockholm
Summary
Tai Chi combines strength and neuromuscular training with diaphragmatic breathing, attention, imagery and relaxation. After an initial learning period, participants can practise independently, potentially supporting self-efficacy and sustained self-management. Studies in chronic disease report benefits for physical function and psychological wellbeing.
The investigators will evaluate a 12-week Tai Chi rehabilitation programme in a clincial trial. The Multiple Sclerosis Impact Scale (MSIS-29) is the primary clinical outcome, reflecting the physical and psychological consequences of multiple sclerosis (MS). Assessments take place before training and at 12 weeks (the primary endpoint).
The study will address whether Tai Chi improves physical and mental health; reduces fatigue, anxiety, depression and pain; improves lower-limb strength, gait and balance; and improves quality of life and self-efficacy.
Eligibility Criteria
Inclusion Criteria:
* over 18 years age
* definite MS diagnosis
* ability to walk more than 100 m
* no relapse or pharmacological treatment adjustment in the preceding eight weeks
* no Tai Chi practice in the preceding six months
* ability to understand and communicate in Swedish or English
Exclusion Criteria:
* dementia
* alcoholism
* serious medical comorbidity preventing participation
Source: ClinicalTrials.gov (NCT07890974). StuddyBuddy aggregates publicly available trial information.