Virtual Reality Intervention to Improve Comfort in Hospitalized Hematology Patients

The objective of this clinical trial is to determine whether virtual reality (VR) devices can improve comfort and quality of life in hospitalized adult patients with hematological malignancies who require at least 15 consecutive days of inpatient treatment. The study will include adult patients of both sexes with 18 years or more. The main questions it aims to answer are: * Does the use of virtual reality devices improve the overall comfort of patients hospitalized with hematological malignancies? * Does virtual reality improve patients' quality of life compared to standard clinical care without the use of this technology? * What are the immediate effects of virtual reality on patient well-being, and what potential adverse effects may arise during its use? * How do patients perceive the use of virtual reality during their hospital stay? The researchers will compare two groups: * Group A: Virtual reality intervention: Participants will use virtual reality devices for 15 minutes on days 5, 8, 15, and 22 of the study. They will be able to choose from a selection of virtual natural landscapes, providing an immersive distraction during their hospitalization. * Group B: Control group: Participants will receive standard clinical care without the virtual reality intervention. Participants will be randomly assigned to one of the two groups. Comfort and quality of life will be assessed using the General Comfort Questionnaire (GCQ) and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), both of which will be administered on days 5 and 22 of the study. Additionally, the immediate effects of virtual reality will be evaluated by measuring vital signs and assessing symptoms before and after the intervention, including any potential discomfort, dizziness, or nausea related to the use of this technology. The study aims to recruit approximately 145 participants across three hospitals in Valencia, Spain. The results could help determine whether virtual reality serves as a useful non-pharmacological nursing intervention for improving comfort and well-being during a prolonged hospital stay due to hematological malignancies.

Inclusion Criteria: * Male and female patients, aged 18 or more and different racial backgrounds. * Diagnosed with a hematological condition. * Hospital stay of 15 days or longer to receive treatment for a diagnosed hematological malignancy. Exclusion Criteria: * Language barriers or physical and/or cognitive impairments that prevent patients from understanding the intervention or completing the study assessment tools. * History of photosensitive epilepsy and/or intolerance to virtual reality. * Failure to provide informed consent or withdrawal of informed consent.