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NCT07896070
Impact of Higher Zinc Supplementation on Neonatal Weight Velocity
Conditions: Extreme Prematurity,Extremely Low Birthweight, BPD - Bronchopulmonary Dysplasia, Growth
Sex: All
Ages: 25 Weeks – 34 Weeks
Healthy volunteers: No
Phase: PHASE4
Enrollment: 30
Sponsor: Augusta University
Location: Wellstar Childrens Hospital of Georgia Augusta Georgia
Summary
Preterm infants born prematurely are more likely to have low zinc levels because they have less time to build up zinc before birth. They also have smaller zinc stores after birth and may need more zinc to support their rapid growth.
This study will examine how growth is affected in premature babies receiving either the current dose or a higher dose of zinc supplementation. The zinc supplement will be given daily, starting according to the unit's standard feeding guidelines, and will be stopped based on usual standard-of-care practices.
Possible risks of zinc supplementation include gastrointestinal intolerance (such as vomiting, diarrhea, or stomach discomfort) and anemia.
Possible benefits include improved growth, a stronger immune system, a shorter hospital stay, and lower healthcare costs.
Eligibility Criteria
Inclusion Criteria:
* Birth weight: 750-1500 grams
Exclusion Criteria:
* Spontaneous Intestinal Perforation (SIP)
* Necrotizing enterocolitis (NEC)
* Gastrointestinal anomalies (gastroschisis, omphalocele, or intestinal atresia)
* Infants on formula milk
Source: ClinicalTrials.gov (NCT07896070). StuddyBuddy aggregates publicly available trial information.