EEG Markers From Polysomnography and Cognitive Performance in Obstructive Sleep Apnea

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 100

Sponsor: University of Split, School of Medicine

Summary

This cross-sectional study examines whether EEG markers derived from full-night polysomnography (sleep spindle density, K-complex density, and REM EEG slowing) are associated with cognitive performance in adults with obstructive sleep apnea, and whether they explain more variance in cognitive test scores than classical OSA metrics (AHI, T90, minimal SpO2).

Eligibility Criteria

Inclusion Criteria: * Adults (18 years or older) * Referred for diagnostic full-night polysomnography (PSG) at the Sleep Medicine Center Split * Obstructive sleep apnea confirmed by PSG (apnea-hypopnea index ≥5 events/hour) * Total sleep time greater than 4 hours on PSG * Willing to complete the cognitive test battery * Written informed consent Exclusion Criteria: * Active chronic disease that may substantially affect cognition or sleep architecture (e.g., uncompensated heart failure, malignancy) * Neurological disease * Other sleep disorders * History of head trauma * History of head surgery * Inability to complete cognitive testing adequately

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07897474). StuddyBuddy aggregates publicly available trial information.