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NCT07901491
SUVY VerSus SAccharose (SUVISA)
Conditions: Healthy Volunteers, Erythritol
Sex: All
Ages: 18 Years – 50 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 14
Sponsor: Minerais SAS
Location: Centre d'Investigation Clinique - CHU de Rennes - Hôpital Pontchaillou Rennes Ille-et-Vilaine
Summary
Sugar substitutes are increasingly used to reduce sugar intake. SÜVY is a food ingredient combining erythritol and polydextrose. This study compares the blood sugar response, insulin response, and platelet activity after drinking a solution of SÜVY (50 g) versus a solution of regular sugar (sucrose, 50 g) in 14 healthy adults. Each participant takes part in two visits separated by at least 7 days, receiving one product per visit in random order. The goal is to evaluate whether SÜVY produces a lower blood sugar response than sucrose, and whether it has any effect on blood clotting markers.
Eligibility Criteria
Inclusion Criteria:
* Healthy adult volunteers aged 18 to 50 years
* Body Mass Index (BMI) between 18.5 and 29.5 kg/m²
* Fasting blood glucose \< 1.10 g/L
* HbA1c \< 6.0%
* Non-smoker
* No known hemostatic disorder or thrombotic history
* No antiplatelet, anticoagulant or NSAID medication within 10 days prior to each visit
* Able to provide written informed consent
Exclusion Criteria:
* Diabetes mellitus (type 1 or type 2) or any antidiabetic treatment
* Known intolerance to polyols or irritable bowel syndrome
* Pregnancy or breastfeeding
* Chronic inflammatory disease
* Participation in another clinical study within 3 months prior to inclusion
* Any condition that, in the investigator's judgment, would compromise the participant's safety or the integrity of the study data
Source: ClinicalTrials.gov (NCT07901491). StuddyBuddy aggregates publicly available trial information.