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Not Yet Recruiting NCT07904143

Povidone-Iodine and Ozonated Distilled Water Irrigation in the Management of Maxillofacial Space Infections

Conditions: Infection, Surgical Site

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 26
Sponsor: Alexandria University

Location: Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt Alexandria Azarita

Summary

Maxillofacial space infections are among the most common infections encountered in oral and maxillofacial surgery and may progress to severe, life-threatening complications if not properly managed, making their treatment a critical component of maxillofacial surgical practice(1).In recent years, Ozonated distilled water has emerged as a promising alternative owing to its potent antimicrobial activity against bacteria, viruses, and fungi, while demonstrating minimal toxicity to host tissues.(2-3) Aim: thus, the aim of the present study is to investigate whether ozonated distilled water irrigation in patients experiencing facial space infection after surgical incision and drainage of the maxillofacial space infection would result in resolution of infection, reduction of postoperative pain and reduction of wound size.

Eligibility Criteria

Inclusion Criteria: * Patients with involvement of one or more maxillofacial space infections (suprahyoid) are indicated for incision and surgical drainage after failure of conservative medical treatment. * No gender predilection. Exclusion Criteria: * Secondary space infection due to malignant tumors. * A history of surgical intervention prior to admission. * Pregnant or lactating females. * Medically compromised patients. * Previously drained or recurrent neck infection.

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Source: ClinicalTrials.gov (NCT07904143). StuddyBuddy aggregates publicly available trial information.