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NCT07906561
Serum GDF-15 and LGALS3BP as Prognostic Biomarkers in Sepsis
Conditions: Sepsis, Septic Shock
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 150
Sponsor: Inonu University
Summary
The purpose of this study is to find out whether blood levels of two proteins, GDF-15 and LGALS3BP, measured at intensive care unit admission and at 72 hours, can help predict survival and organ dysfunction in adult patients with sepsis or septic shock. Blood samples are collected together with routine laboratory tests, without additional needle sticks. The study does not change patient treatment.
Eligibility Criteria
Inclusion Criteria:
* Age 18 years or older
* Sepsis or septic shock according to Sepsis-3 criteria
* Enrollment possible within 24 hours of ICU admission
Exclusion Criteria:
* Chronic heart failure (NYHA class III-IV)
* Stage 4-5 chronic kidney disease or maintenance dialysis
* Active malignancy or chemotherapy/radiotherapy within the last 6 months
* Pregnancy
* Expected death or discharge within 24 hours of ICU admission
* Refusal to participate -
Source: ClinicalTrials.gov (NCT07906561). StuddyBuddy aggregates publicly available trial information.
