THE EFFECT OF FILLING MATERIAL AND PLACEMENT TECHNIQUE ON POSTOPERATIVE PAIN IN NON-SURGICAL ENDODONTIC RETREATMENT: A RANDOMIZED CLINICAL TRIAL

Postoperative pain is a common concern following root canal retreatment. The type of root canal filling material and the technique used to place it may influence pain experienced after treatment. This randomized clinical trial aims to compare the effects of two calcium silicate-based root canal filling materials (BioMTA+ and Well-Root PT) and two placement techniques (manual compaction and reverse-rotation compaction) on postoperative pain following nonsurgical endodontic retreatment. A total of 56 adult patients requiring root canal retreatment due to persistent inflammation around the root tip will be randomly assigned to four treatment groups. All procedures will be performed in a single visit. Postoperative pain will be evaluated using a visual analog scale (VAS), and the use of pain-relieving medication will be recorded. The study aims to determine whether the type of filling material, the placement technique, or their combination influences postoperative pain following nonsurgical root canal retreatment.

\*\*Inclusion Criteria:\*\* * Patients aged 18-65 years with ASA physical status I-II. * Patients who have not used analgesics or antibiotics within the previous 7 days. * Patients with previously root canal-treated, single-rooted permanent teeth requiring nonsurgical endodontic retreatment. * Teeth exhibiting radiographic evidence of loss of apical constriction or an enlarged apical foramen. * Patients with clinically and radiographically diagnosed apical periodontitis. * Teeth that are restorable and do not require extraction. \*\*Exclusion Criteria:\*\* * Patients with diabetes mellitus, immunosuppression, pregnancy, or other medically compromising conditions requiring medication. * Patients requiring antibiotic prophylaxis. * Patients with known allergies to materials used during root canal treatment. * Patients with known allergies to analgesics or antibiotics. * Teeth with calcified root canals or internal or external root resorption. * Teeth with immature open apices.