Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Sphenopalatine Ganglion Block for Functional Endoscopic Sinus Surgery

Conditions: Post Operative Pain, Emergence Agitation, Functional Endoscopic Sinus Surgery

Sex: All

Ages: 18 Years – 60 Years

Healthy volunteers: No

Phase: PHASE4

Enrollment: 60

Sponsor: Sohag University

Summary

This prospective, randomized, double-blind, controlled trial will compare the efficacy and safety of dexmedetomidine versus dexamethasone as adjuvants to bupivacaine in ultrasound-guided bilateral sphenopalatine ganglion block for adult patients (18-60 years, ASA I-II) undergoing elective functional endoscopic sinus surgery (FESS) under general anesthesia. Participants will be randomly allocated in a 1:1:1 ratio to receive bupivacaine alone, bupivacaine plus dexmedetomidine, or bupivacaine plus dexamethasone. The study will assess postoperative pain scores, duration of analgesia, total analgesic consumption, and intraoperative hemodynamic parameters, in addition to adverse effects.

Eligibility Criteria

Inclusion Criteria: * Age 18-60 years. * Elective FESS under general anesthesia. * ASA Physical Status I-II Exclusion Criteria: * Allergy to local anesthetics * Coagulopathy or use of anticoagulants * Anatomical nasal deformities obstructing access * Patient refusal

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07911202). StuddyBuddy aggregates publicly available trial information.