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NCT07917533
Is Routine Dental Clearance or Antibiotic Prophylaxis Before Dental Procedures Necessary in Total Joint Arthroplasty? A Randomized Controlled Noninferiority Trial
Conditions: Elective Primary THA or TKA
Sex: All
Ages: 19 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 3048
Sponsor: Creighton University
Summary
This study is a prospective, randomized, controlled, noninferiority trial with parallel assignment that will afford simultaneous assessment of the omission of dental clearance and the omission of post-operative antibiotics for dental procedures.
Eligibility Criteria
Inclusion Criteria
* Age ≥19 years (19 is age of majority in Nebraska)
* Scheduled for elective primary THA or TKA (i.e. no revision or conversion procedures)
* Ability to provide informed consent
Exclusion Criteria
* Revision arthroplasty
* Arthroplasty for fracture or performed urgently (i.e. incomplete work up)
* Active or previous infection of the operative joint
* Active systemic infection
* On chronic antibiotic therapy
All patients who meet the above criteria will be offered inclusion in the study either at their pre-operative clinic visit or over the phone.
Source: ClinicalTrials.gov (NCT07917533). StuddyBuddy aggregates publicly available trial information.