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Not Yet Recruiting NCT07917533

Is Routine Dental Clearance or Antibiotic Prophylaxis Before Dental Procedures Necessary in Total Joint Arthroplasty? A Randomized Controlled Noninferiority Trial

Conditions: Elective Primary THA or TKA

Sex: All
Ages: 19 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 3048
Sponsor: Creighton University

Summary

This study is a prospective, randomized, controlled, noninferiority trial with parallel assignment that will afford simultaneous assessment of the omission of dental clearance and the omission of post-operative antibiotics for dental procedures.

Eligibility Criteria

Inclusion Criteria * Age ≥19 years (19 is age of majority in Nebraska) * Scheduled for elective primary THA or TKA (i.e. no revision or conversion procedures) * Ability to provide informed consent Exclusion Criteria * Revision arthroplasty * Arthroplasty for fracture or performed urgently (i.e. incomplete work up) * Active or previous infection of the operative joint * Active systemic infection * On chronic antibiotic therapy All patients who meet the above criteria will be offered inclusion in the study either at their pre-operative clinic visit or over the phone.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07917533). StuddyBuddy aggregates publicly available trial information.