← Back to all trials
Not Yet Recruiting
NCT07922174
A Clinical Trial of MK-6916 in Participants With Moderate and Severe Kidney Disease Compared to Healthy Controls (MK-6916-013)
Conditions: Healthy, Renal Impairment
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 32
Sponsor: Merck Sharp & Dohme LLC
Summary
The purpose of this study is to learn what happens to MK-6916 in a person's body when given to participants with moderate or severe kidney impairment compared to healthy participants.
Eligibility Criteria
Inclusion Criteria:
The main inclusion criteria include but are not limited to the following:
Moderate and Severe Renal Impairment
* Except for severe or moderate renal impairment, is sufficiently healthy for study participation
* Has stable renal function Healthy
* Matches mean age to participants with moderate and severe renal impairment
Exclusion Criteria:
The main exclusion criteria include but are not limited to the following:
All participants
* Has history of cancer (malignancy)
* Has positive test(s) for hepatitis B surface antigen (HBsAg), hepatitis C antibodies, or human immunodeficiency virus (HIV)
* Has had major surgery and/or donated or lost 1 unit of blood within 4 weeks prior to pretrial Participants with Renal Impairment
* Has a history of renal artery stenosis, failed renal transplant or has had a nephrectomy, or end stage renal disease requiring dialysis
Source: ClinicalTrials.gov (NCT07922174). StuddyBuddy aggregates publicly available trial information.