← Back to all trials
Active Not Recruiting
NCT07929454
Evaluation of Orthodontic Bands Coated With Nano-silver Fluoride
Conditions: White Spot Lesion of Tooth, Pocket, Periodontal, Dental Caries Tooth Demineralization
Sex: All
Healthy volunteers: Yes
Phase: NA
Enrollment: 25
Sponsor: Ebrahim N Abbas
Location: Mansoura university Al Mansurah
Summary
1. Aim of the Study To evaluate the antibacterial and enamel remineralization effects of nano-silver fluoride-coated orthodontic bands compared with conventional non-coated bands in orthodontic patients over 6 months.
2. What Will I Do in This Study?
* Conduct a randomized split-mouth clinical trial involving 25 patients.
* Place orthodontic bands on the maxillary first molars, with one band coated and the contralateral band left uncoated as the control.
* Randomize the right or left side receiving the coated band.
* Collect dental plaque samples after 24 hours, 3 months, and 6 months to measure bacterial counts, particularly Streptococcus mutans, using colony-forming unit (CFU) counting.
* Assess enamel demineralization and remineralization using DIAGNOdent measurements before band placement and after band removal.
3. Materials Used
* Orthodontic bands: Stainless steel molar bands.
* Silver nanoparticles (AgNPs): Concentration of 5 µg/mL, with an average particle size of 40 nm.
* Fluoride: Concentration of 5 ppm.
* Coating technique: Dip coating, followed by air-drying and incubator drying.
Eligibility Criteria
Inclusion Criteria:
* • Patients presenting with malocclusion, including crowding, spacing, increased overjet or overbite, crossbite, or open bite.
* Presence of a sufficient number of erupted permanent teeth to allow effective placement and retention of orthodontic appliances.
* Good oral and periodontal health, with no active caries or untreated periodontal disease.
* Systemically healthy patients, or those with controlled medical conditions that do not contraindicate orthodontic tooth movement.
* Patients demonstrating adequate motivation and willingness to cooperate, including maintaining oral hygiene and attending regular follow-up visits.
Exclusion Criteria:
* • Presence of active dental caries or Poor oral hygiene.
* Active periodontal disease, including gingivitis or periodontitis with attachment loss.
* Patients with uncontrolled systemic diseases that may affect bone metabolism or healing (e.g., uncontrolled diabetes, metabolic bone disorders).
* Use of medications that adversely affect orthodontic tooth movement and cannot be medically managed.
* Insufficient erupted teeth to support orthodontic appliances.
* Low motivation or poor compliance, including failure to attend appointments or follow treatment instructions.
Source: ClinicalTrials.gov (NCT07929454). StuddyBuddy aggregates publicly available trial information.