← Back to all trials
Not Yet Recruiting
NCT07931755
Early Laparoscopic Cholecystectomy for Mild Gallstone Pancreatitis
Conditions: Mild Gallstone Pancreatitis, Acute Pancreatitis, Gallstones, Cholelithiasis
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 50
Sponsor: Sohag University
Location: Sohag University Hospital Sohag
Summary
The purpose of this study is to evaluate the clinical, surgical, and postoperative outcomes of early laparoscopic cholecystectomy performed during the index hospital admission in adult patients presenting with mild gallstone pancreatitis.
Gallstone disease represents a primary cause of acute pancreatitis. While definitive cholecystectomy is essential to prevent recurrent biliary complications, the optimal timing has often been debated. Current guidelines advocate for same-admission cholecystectomy once the acute pancreatitis subsides; however, concerns regarding inflammation, adhesions around Calot's triangle, and potential surgical difficulty frequently influence practical decision-making. This study assesses the overall safety, feasibility, conversion rates to open surgery, complication profile, hospital stay, and recurrence rates among patients managed at Sohag University Hospital.
Eligibility Criteria
Inclusion Criteria:
* Adult patients aged 18 years or older.
* Patients diagnosed with acute pancreatitis based on clinical, laboratory, and/or radiological criteria.
* Evidence of gallstone disease demonstrated by abdominal ultrasonography or other appropriate imaging.
* Mild acute pancreatitis according to the Revised Atlanta Classification, with no organ failure and no local or systemic complications.
* Patients planned for early laparoscopic cholecystectomy during the same index hospital admission.
Exclusion Criteria:
* Moderate or severe acute pancreatitis according to the Revised Atlanta Classification.
* Presence of persistent organ failure, pancreatic necrosis, pseudocyst, or significant peripancreatic fluid collection.
* Acute cholangitis or persistent common bile duct obstruction requiring urgent ERCP before definitive surgery.
* Contraindication to general anesthesia or laparoscopic surgery.
* Pregnancy.
* Previous history of cholecystectomy.
Source: ClinicalTrials.gov (NCT07931755). StuddyBuddy aggregates publicly available trial information.