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Not Yet Recruiting NCT07931794

EFFECTS OF PHASE I PERIODONTAL THERAPY IN CIGARETTE SMOKERS, HEATED TOBACCO PRODUCT USERS, DUAL USERS, AND NON-SMOKERS

Conditions: Generalized Gingivitis, Tobacco Use, Cigarette Use

Sex: All
Ages: 18 Years – 35 Years
Healthy volunteers: No
Phase: NA
Enrollment: 140
Sponsor: Cyprus Health and Social Sciences University

Location: Cyprus Health and Social Sciences University, Faculty of Dentistry Mórfou Northern Cyprus

Summary

This prospective, comparative clinical study aims to evaluate the periodontal status and response to Phase I periodontal therapy among conventional cigarette smokers, heated tobacco product users, dual users of conventional cigarettes and heated tobacco products, and non-smokers. The study includes systemically healthy individuals aged 18-35 years diagnosed with generalized gingivitis. Participants are categorized into four groups according to their existing tobacco use habits. Periodontal assessments include full-mouth plaque score (FMPS), bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment level (CAL). All participants receive conventional Phase I periodontal therapy and standardized oral hygiene instructions as part of routine periodontal care. Clinical periodontal parameters are evaluated at baseline and at one and three months following treatment. The study aims to compare periodontal outcomes and changes over time among the four tobacco use groups.

Eligibility Criteria

Inclusion Criteria: Individuals aged 18-35 years. Systemically healthy individuals. Individuals diagnosed with generalized gingivitis. Individuals belonging to one of the following four groups: Conventional cigarette smokers. Heated tobacco product (HTP) users. Dual users of conventional cigarettes and heated tobacco products. Non-users of tobacco products. Individuals who voluntarily agree to participate in the study and provide written informed consent. Exclusion Criteria: Individuals with a current or previous diagnosis of periodontitis. Individuals currently undergoing orthodontic treatment. Individuals using medications that may affect periodontal health. Individuals who have used antibiotics within the previous 3 months. Pregnant or breastfeeding individuals. Individuals who have received periodontal treatment within the previous 6 months. Individuals with current alcohol dependence.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07931794). StuddyBuddy aggregates publicly available trial information.