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NCT07932171
Carotid Ultrasound-based Assessment of Maternal Hemodynamics to Guide HYpertension Treatment in PREgnancy - Pilot Study
Conditions: Hypertensive Disorders of Pregnancy (HDP), Pregnancy
Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 200
Sponsor: Assistance Publique - Hôpitaux de Paris
Location: Hôpital Antoine Béclère Clamart Clamart
Summary
Carotid ultrasound-based assessment of maternal hemodynamics to guide HYpertension treatment in PREgnancy - Pilot study - CHYPRE-pilot Healthy pregnancy is associated with significant physiological hemodynamic changes that are critical for maternal adaptation and health. Insufficient adaptive changes can lead to pregnancy disorders such as preeclampsia. Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal and foetal morbidity and mortality. Assessment of maternal hemodynamic alterations can improve management strategies by better risk stratification of pregnant women. Current methods for maternal hemodynamic measurement involve transthoracic echocardiography, requiring expert consultation with a cardiologist and highly trained staff. Simpler techniques like carotid ultrasound based hemodynamic assessment can potentially provide an easy-to perform alternative, requiring minimal training.
Eligibility Criteria
Inclusion criteria:
* Pregnant women \> 18 years of age
* Singleton pregnancy
* 10th to 40th week of pregnancy
* Patients affiliated with social security or an equivalent scheme
* Signed informed consent
Exclusion criteria:
* Multifoetal pregnancy
* Known allergies to ultrasound gel
* Patient on AME (state medical aid)
* Patient under a legal protection measure: guardianship, curatorship, or judicial safeguard.
Source: ClinicalTrials.gov (NCT07932171). StuddyBuddy aggregates publicly available trial information.