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NCT07936591
First-Trimester Ultrasound Assessment of Velamentous Cord Insertion
Conditions: Prenatal Diagnosis
Sex: Female
Ages: 18 Years – N/A
Healthy volunteers: Yes
Enrollment: 1000
Sponsor: Hospital Authority, Hong Kong
Location: Pamela Youde Nethersole Eastern Hospital Hong Kong
Summary
The goal of this observational study is to learn whether a short ultrasound assessment during the routine first-trimester pregnancy scan can identify velamentous cord insertion, an abnormal location where the umbilical cord joins the placenta. The study will include pregnant participants aged 18 years or older with a singleton pregnancy who attend first-trimester combined screening between 11+0 and 13+6 weeks of pregnancy.
The main questions it aims to answer are:
* How often can the placental cord-insertion site be successfully classified within a 3-minute assessment?
* How accurately does first-trimester ultrasound identify velamentous cord insertion compared with examination of the placenta after delivery?
Participants will:
* Attend their usual first-trimester ultrasound examination.
* Have an additional transabdominal ultrasound assessment of the placental cord-insertion site after the routine scan, taking no more than 3 minutes.
* Allow the study team to review relevant pregnancy and birth records.
* If they deliver at the study hospital, allow examination of the placenta after delivery as part of the study reference standard.
Eligibility Criteria
Inclusion Criteria:
* Pregnant participants aged 18 years or older with a singleton pregnancy
* Attendance for first-trimester combined screening at 11+0 to 13+6 weeks
* Capacity to provide written informed consent
Exclusion Criteria:
* Multiple pregnancy
* Declined or withdrawn consent
Source: ClinicalTrials.gov (NCT07936591). StuddyBuddy aggregates publicly available trial information.