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NCT07936786
HIIT-based Exercise Intervention for Improvement of Immunomodulatory, Cardiopulmonary, and Psychosocial Parameters During Maintenance Therapy of Paediatric Acute Lymphoblastic Leukaemia (HEALL)
Conditions: Leukemia, HIIT, Sport
Sex: All
Ages: 6 Years – 10 Years
Healthy volunteers: No
Phase: NA
Enrollment: 108
Sponsor: University of Erlangen-Nürnberg Medical School
Location: University Hospital Erlangen, Department for childhood and adolescence medicine Erlangen Baveria
Summary
In this study, the investigators aim to examine the effects of high-intensity interval training (HIIT) on cardiopulmonary fitness and immunological recovery in female ALL survivors who underwent cancer treatment during childhood and adolescence.
Eligibility Criteria
Inclusion Criteria:
* Diagnosed acute lymphatic leukemia
* Begin of maintenance therapy
* From 6 to 10 years of age
* Physical ability to participate in HIIT and cardiopulmonary exercise testing
Exclusion Criteria:
* Known pleural or pericardial effusion
* Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure)
* Marked thoracic deformities/malformations
* Previous lung surgery
* Injuries that do not allow physical stress diagnostics
Source: ClinicalTrials.gov (NCT07936786). StuddyBuddy aggregates publicly available trial information.
